Allergen extracts made in Germany

The Supplier for Allergy Test Producers
The Labor Dr. Weyers is a german company with long-standing experience in the production of precursors for Allergy diagnosics (Type-I-Allergy) as well as bee and wasp venoms for Allergy therapeutics.

Welcome to www.allergenextract.de – Labor Dr. Weyers

Very valued customers,
now you will find us in the world wide web with our propositions around allergy diagnostics an allergy therapeutics.

We offer:
-hundreds of allergens – standard allergens as well as custom-made products – for allergy-tests, see our allergen catalogue
-highly pure insect-venoms for the production of allergy therapeutics
-the take over of individual steps of the production of the test- and kit-manufacturing

Our Propositions
We are your specialist for allergen extracts and for the issue of ‘stinging insects’. We are a business, which has been offering services concerning the issue of ‘stinging insects’ since 1992: We provide advice for problems with bee-, bumble-bee-, wasp- and hornet- colonies, we relocate these type of colonies on demand and obtain venom of such kind, in order to provide these as extracts for diagnosis suppliers along with the entire line-up of allergenic substances.
Our area of expertise is the obtainment of highly pure bee-venom and wasp-venom in quantities that also have been approved for the use of allergy therapeutics. Alongside those allergens in the catalog, we also make further extracts of rare allergens, since we are capable of obtaining almost every raw material.
A special service of ours that we offer to any customer is to book a custom batch production on demand of any allergen extracts – if required after the test of a free sample.
For the field of allergy therapy, the subcutaneous specific immunotherapy (SCIT) or also referred to as allergen-desensitizing treatment, we offer highly pure bee-venom and wasp-venom. We obtain venoms from living animals through electric stimulation, whereby we have developed a method, which guarantees, that these venoms are separated in an absolute contaminant free environment. The single venom doses are merged to larger portions and are lyophilised afterwards. In this state the material is preserved safely for a period of many years, while the activity of the venom’s enzymes remains fully intact. This proves the high purity and the indulgent processing of these hard-to-make resources. Furthermore the high activity of enzymes in our venoms provides a great level of yield compared to competing preparations that are most likely obtained from venom sac preparations.
The high purity of our venoms also ensures an excellent medication tolerance for the patient during in vivo application. Thus it is no surprise that successful medical studies have already been conducted with our venoms.
We would be happy to provide you with free samples, so you can convince yourself of the high quality of our products.

Allergen extracts – our offering
Our allergen extracts offering is aimed at producers of in-vitro tests for the diagnosis of type I allergies.
Our allergen catalog includes several hundred allergens, which we constantly keep ready for our customers and which cover the areas of job-allergens, woods, house dust mites, storage mites, animal hair, epithelial tissues of animals, bird feathers, animal excrements, animal serums, food, grass pollen, grain pollen, household dust, insect venoms, entire insects, horse allergens, molds, yeasts, bacteria, parasites, spices, tree pollen, shrub pollen and weed pollen.
In case a demanded allergen can’t be found in our catalog, please feel free to contact us. We are happy to provide custom solutions for our customers. With our widely ranging connections we can acquire almost any resource.
A special service of ours that we offer to any customer is to book a custom batch production on demand of any allergen extracts – if required after the test of a free sample.
According to a well-proven procedure the natural materials are leached out in a weakly alkaline range, filtered and dialyzed against PBS (and PBS/Glycerol respectively) in a way, that the extracts include all relevant allergens.
Insect venoms are primarily obtained in pure state through electro stimulation; they are supplied natively just like animal serums.
Upon request, almost every allergen extracts can be lyophilised. The storage life of the liquid form of extract is 3 to 5 years; lyophilised extracts are applicable for the production of allergy tests for up to 15 years.
For customers, whose tests work with biotinylated allergens, we offer a coupling between biotin and our allergens.
All processing steps are recorded. In case of the procurement of external resources the quality of these substances is certified through analysis certificates. Our own production of resources is done under reasonable inspections of character, freshness and material purity. Operational reliability of the extracts for the particular test system of the customer can be checked by testing free samples. Upon request we make test disks of the extracts and determine the operational reliability with positive-serum in combination with our own reference extracts.
In agreement with our customers we also offer to take over single processing steps for the manufacture of tests – be it the chemical activation of the coupling medium, the allergen coupling, several quality inspection steps, the portioning of the finished tests in packing units or the compilation of entire kits.

Chemical- and drug-HSA-conjugates
We couple active drug ingredients and job- as well as industry-chemicals, so called haptens, to human serum albumin (HSA). Hapten-protein-conjugates that result from this process can basically be used for the making of allergy diagnostics.
In general bifunctional reagents are used for the coupling. For customers, whose tests work with biotinylated allergens, we offer a coupling between biotin and our allergens.

Allergy Therapy – We offer high quality insect venoms
Our area of expertise is the obtainment of high purity bee- and wasp-venom. With regards to the honey bee, the common wasp (Vespula vulgaris) and the german wasp (Vespula germanica) these natural products are approved to be used for therapeutics, so that many patients can prevent systemic reactions and life threatening situations.
In case of an insect sting allergy a random insect sting often results in immediate allergic reactions, that are often not only locally limited, but can also cause whole-body symptoms. In the worst case scenario a sting can even cause an anaphylactic shock, which is a life threatening situation for the patient.
The insect sting allergy affects about 3 percent of the population of Germany which is roughly 2.4 million people. Every year thousands of those affected, have to be treated by an emergency doctor – nevertheless in two dozens of these incidents any help was too late. In addition experts assume that a considerable estimated number of unknown allergy related deaths exist. In these cases, as with many other Allergies, subcutaneous specific immunotherapy (SCIT) is widely accepted as the only causal treatment for allergies that can prevent the allergic march to asthma and new allergies/sensitizations (long-term efficacy).
We obtain venoms from living animals through electric stimulation, whereby we have developed a method, which guarantees that these venoms are separated in an absolute contaminant free environment. The single venom doses are merged to larger portions and are lyophilised afterwards. In this state the material is preserved safely for a period of many years, while the activity of the venom’s enzymes remains fully intact. This proves the high purity and the indulgent processing of these hard-to-make resources. Furthermore the high activity of enzymes in our venoms provides a great level of yield compared to competing preparations that are most likely obtained from venom sac preparations.

The high purity of our venoms also ensures an excellent medication tolerance for the patient during in vivo application. Thus it is no surprise that successful medical studies have already been conducted with our venoms.

We would be happy to provide you with free samples, so you can convince yourself of the high quality of our products.

If you are interested in our products or if you have any further questions you are more than welcome to contact us.

You can send us an e-mail (we would prefer): labor.dr.weyers(at)gmx.de

or you can call us anytime under 0049-241-9513525.

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